@article {Liu:2006:0960-7412:260,
title = "Intracellular K+ sensing of SKOR, a Shaker -type K+ channel from Arabidopsis",
journal = "The Plant Journal",
parent_itemid = "infobike://bsc/tpj",
publishercode ="bp",
year = "2006",
volume = "46",
number = "2",
publication date ="2006-04-01T00:00:00",
pages = "260-268",
itemtype = "ARTICLE",
issn = "0960-7412",
eissn = "1365-313X",
url = "https://www.ingentaconnect.com/content/bsc/tpj/2006/00000046/00000002/art00008",
doi = "doi:10.1111/j.1365-313X.2006.02689.x",
keyword = "giant patch, K+ sensing, K+ channel, two-electrode voltage clamp",
author = "Liu, Kun and Li, Legong and Luan, Sheng",
abstract = "Summary Most K+ channels in plants are structurally classified into the Shaker family named after the shaker K+ channel in Drosophila. Plant K+ channels function in many physiological processes including osmotic regulation and K+ nutrition. An outwardly rectifying K+ channel, SKOR, mediates the delivery of K+ from stelar cells to the xylem in the roots, a critical step in the long-distance distribution of K+ from roots to the upper parts of the plant. Here we report that SKOR channel activity is strictly dependent on intracellular K+ concentrations. Activation by K+ did not affect the kinetics of voltage dependence in SKOR, indicating that a voltage-independent gating mechanism underlies the K+ sensing process. Further analysis showed that the C-terminal non-transmembrane region of the SKOR protein was required for this sensing process. The intracellular K+ sensing mechanism couples SKOR activity to K+ nutrition status in the source cells, thereby establishing a supply-based unloading system for the regulation of K+ distribution.",
}