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Free Content Atorvastatin reduces T‐cell activation and exhaustion among HIV‐infected cART‐treated suboptimal immune responders in Uganda: a randomised crossover placebo‐controlled trial

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T‐cell activation independently predicts mortality, poor immune recovery and non‐AIDS illnesses during combination antiretroviral therapy (cART). Atorvastatin showed anti‐immune activation effects among HIV‐infected cART‐naïve individuals. We investigated whether adjunct atorvastatin therapy reduces T‐cell activation among cART‐treated adults with suboptimal immune recovery.
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Keywords: HIV/AIDS; VIH/SIDA; activación inmune; activation immunitaire; adjunct therapy; antiretroviral therapy; atorvastatin; atorvastatina; atorvastatine; immune activation; immune recovery; reconstitution immunitaire; recuperación inmune; terapia adjunta; terapia antirretroviral; thérapie antirétrovirale; traitement d'appoint

Document Type: Research Article

Publication date: March 1, 2015

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