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Free Content Durable HIV RNA resuppression after virologic failure while remaining on a first‐line regimen: a cohort study

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Adherence interventions are a recommended strategy to salvage failing antiretroviral therapy without regimen change. We assessed the durability of resuppression when using this approach. Of 300 patients who resuppressed on the same regimen (41% of all those with virologic failure), 148 (45%) remained suppressed during follow‐up for a median of 2.4¬†years (interquartile range [IQR]: 1.1, 4.0). Resuppression can be durable following viraemia without a switch in antiretroviral therapy regimen.
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Keywords: Africa; HIV; adherence; antiretroviral therapy; clinical management; treatment failure

Document Type: Research Article

Publication date: February 1, 2014

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