Skip to main content
padlock icon - secure page this page is secure

Short communication: Comparison of serology and isolates for the identification of infecting leptospiral serogroups in Hawaii, 1979–1998

Buy Article:

$52.00 + tax (Refund Policy)


Laboratory confirmation of leptospirosis is usually accomplished serologically, without isolates, using the microscopic agglutination test (MAT). However, optimal performance of the MAT is dependent on the knowledge of enzootic serogroups and serovars so that an appropriate MAT antigen testing battery can be established. Infecting leptospiral serogroups can be identified serologically without isolates, using the MAT, or by serogrouping of isolates, but little information is available regarding the correlation between these methods. The identification of infecting serogroups for 53 culture-confirmed leptospirosis cases, diagnosed in Hawaii between 1979 and 1998, using serology and culture isolates were compared. The overall agreement between the two methods was good ( = 0.71, 95% CI: 0.56, 0.86). However, the agreement varied between serogroups from 0 to 100%. In establishing the prevalence of serogroups, results obtained via MAT serology (in the absence of serogrouped isolates) should be considered presumptive rather than definitive.
No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Keywords: Hawaii; laboratory techniques and procedures; leptospirosis; zoonosis

Document Type: Short Communication

Affiliations: 1: Department of Public Health Sciences and Epidemiology, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI, USA 2: Epidemiology Branch, Communicable Disease Division, Hawaii State Department of Health, Honolulu, HI, USA 3: Kaiser Permanente Medical Care Program, Koolau Clinic, Kaneohe, HI, USA

Publication date: July 1, 2003

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more