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Hypoglycemia as a Result of Propranolol During Treatment of Infantile Hemangioma: A Case Report

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Abstract: 

Propranolol is a new and promising treatment for hemangiomas of infancy. We report of a patient in whom steroid maintenance therapy is successfully tapered after introduction of propranolol. This patient, however, developed symptomatic hypoglycemic events presumably because of a concurrent deficiency of epinephrine and cortisol as a direct result of both beta-blockage by propranolol and adrenal insufficiency as a result of prednisone use. Extreme care should be taken in patients treated with both propranolol and prednisone as they are at increased risk of hypoglycemia.
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Document Type: Research Article

Affiliations: 1: Department of Pediatric Cardiology, Centre for Congenital Vascular Anomalies Utrecht, University Medical Centre Utrecht/Wilhelmina Children’s Hospital, Lundlaan, Utrecht, The Netherlands 2: Department of Pediatric Dermatology & Allergology, Centre for Congenital Vascular Anomalies Utrecht, University Medical Centre Utrecht/Wilhelmina Children’s Hospital, Lundlaan, Utrecht, The Netherlands 3: Department of Pediatric Plastic Surgery, Centre for Congenital Vascular Anomalies Utrecht, University Medical Centre Utrecht/Wilhelmina Children’s Hospital, Lundlaan, Utrecht, The Netherlands

Publication date: March 1, 2011

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