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Bacillus Calmette-Guérin Vaccine-Induced Lupus Vulgaris in a Child Adopted from China

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Abstract: 

Lupus vulgaris is a rare form of cutaneous mycobacterial infection that can occur from mycobacterial exposure and even more rarely from exposure to the Bacillus Calmette-Guérin vaccine. We report a child who received this vaccination in China and then developed lupus vulgaris shortly after being adopted in the United States. After histopathologic confirmation, the infection was successfully treated with a combination of antibiotics. This occurrence demonstrates the need for heightened surveillance of Bacillus Calmette-Guérin vaccine-induced lupus vulgaris, given the increasing numbers of overseas adoptions taking place in the United States. To our knowledge, this is the first reported instance of Bacillus Calmette-Guérin immunization-induced lupus vulgaris in the United States.
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Document Type: Research Article

Affiliations: 1: Dermatology 2: Pediatrics, Baylor College of Medicine, Houston, Texas

Publication date: September 1, 2007

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