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Disseminated fusariosis by Fusarium proliferatum in a patient with aplastic anaemia receiving primary posaconazole prophylaxis – case report and review of the literature

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Disseminated fusariosis is a life‐threatening, invasive, opportunistic infection in immunocompromised patients, especially those with haematological malignancies. The prognosis is poor because these fungi are resistant to many of the available antifungal agents. We present a case of disseminated fusariosis caused by Fusarium proliferatum in a patient with severe aplastic anaemia complicated by a secondary infection of Aspergillus flavus, with a fatal outcome. We also review the documented Fusarium infections in immunocompromised hosts.
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Keywords: Fusarium proliferatum; PCR diagnostics; fusariosis; real‐time PCR

Document Type: Research Article

Publication date: January 1, 2016

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