Comparison of in vitro activities of antifungal drugs and ethanolic extract of propolis against Trichophyton rubrum and T. mentagrophytes by using a microdilution assay
The in vitro activities of propolis against 29 strains of dermatophytes were compared with those of terbinafine, itraconazole, ketoconazole, and fluconazole. Minimal inhibitory concentrations (MICs) were determined according to a National Committee for Clinical Laboratory Standards broth microdilution method. Among the systemic antifungals tested, terbinafine was the most potent. Propolis showed important antifungal activity and it merits further investigation as a potentially useful agent for the treatment of dermatophytosis.
Document Type: Research Article
Affiliations: 1: Medical Faculty, Department of Microbiology, Erciyes University, Kayseri 2: Department of Animal Science, S.Çıkrıkçıogˇlu Vocational College, Erciyes University, Kayseri 3: Medical Faculty, Department of Dermatology, Erciyes University, Kayseri 4: Faculty of Agriculture, Department of Animal Science Biometry and Genetics, Çukurova University, Adana, Turkey
Publication date: May 1, 2005