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Influence of Serum on in Vitro Digestion of Paracoccidioides brasiliensis by Neutrophils

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Serum from patients with paracoccidioidomycosis (PARA) did not block digestive abilities of neutrophils (PMNs) from healthy individuals against Paracoccidioides brasiliensis. Conversely, serum from healthy donors did not enhance digestive capacities of PMNs from patients with PARA vis á vis the causative organism. We conclude that the specific digestive defect present in PMNs from patients with PARA is not mediated by serum factors.
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Keywords: Granulozyten-Abbaudefekt; Paracoccidioides brasiliensis; Paracoccidioidomykose; granulocyte digestive defect; neutrophils; paracoccidioidomycosis; polymorphkernige Granulozyten

Document Type: Research Article

Affiliations: 1: Sections of Immunology 1 and Mycology, Institute de Biomedicina, Central University of Venezuela, Caracas, Venezuela 2: Instituto Nacional de Tuberculosis and Hospital Simon Bolivar, Ministerio de Sanidad y Asistencia Social, Caracas, Venezuela

Publication date: March 1, 1990

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