Archaea and the cell cycle
Sequence similarity data suggest that archaeal chromosome replication is eukaryotic in character. Putative nucleoid-processing proteins display similarities to both eukaryotic and bacterial counterparts, whereas cell division may occur through a predominantly bacterial mechanism. Insights into the organization of the archaeal cell cycle are therefore of interest, not only for understanding archaeal biology, but also for investigating how components from the other two domains interact and work in concert within the same cell; in addition, archaea may have the potential to provide insights into eukaryotic initiation of chromosome replication.
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Document Type: Research Article
Affiliations: Department of Microbiology, Box 581, Biomedical Centre, Uppsala University, S-751 23 Uppsala, Sweden.
Publication date: August 1, 1998