Skip to main content
padlock icon - secure page this page is secure

Familial colorectal cancer

Buy Article:

$52.00 + tax (Refund Policy)

Identifying individuals with a genetic predisposition to developing familial colorectal cancer (CRC) is crucial to the management of the affected individual and their family. In order to do so, the physician requires an understanding of the different gene mutations and clinical manifestations of familial CRC. This review summarises the genetics, clinical manifestations and management of the known familial CRC syndromes, specifically Lynch syndrome, familial adenomatous polyposis, MUTYH‐associated neoplasia, juvenile polyposis syndrome and Peutz–Jeghers syndrome. An individual suspected of having a familial CRC with an underlying genetic predisposition should be referred to a familial cancer centre to enable pre‐test counselling and appropriate follow up.
No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Keywords: adenomatous polyposis coli; colorectal neoplasm; hereditary; hereditary nonpolyposis; neoplastic syndrome

Document Type: Research Article

Publication date: May 1, 2015

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more