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Fabry disease and Factor V Leiden: a potent vascular risk combination

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Abstract

A 45-year-old man with heterozygous Factor V Leiden presented with his third cerebrovascular accident despite being on warfarin at a therapeutic international normalized ratio. Subsequent investigation revealed a second genetic diagnosis of Fabry disease. He then had an acute myocardial infarction whilst on aspirin and warfarin.
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Keywords: Fabry disease; Factor V Leiden; stroke

Document Type: Research Article

Publication date: May 1, 2011

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