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Acute copper toxicity following copper glycinate injection

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We present a patient who developed multi-organ failure due to severe copper toxicity following attempted suicide by s.c. injection of copper glycinate. Acute copper toxicity is rare in the developed world, although it occurs more frequently in developing world countries, where it is a common mode of suicide. Acute toxicity usually results from oral ingestion and there are several local and systemic effects. Specific management can be difficult as there is little evidence regarding the efficacy of chelating agents in acute toxicity.
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Keywords: chelating agent; copper; glycine; penicillamine; s.c. injection

Document Type: Research Article

Affiliations: 1: Department of Cardiothoracic Surgery, St Vincent's Hospital, Fitzroy 2: Department of Intensive Care, Epworth Hospital, Richmond, Victoria, Australia

Publication date: November 1, 2006

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