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Rituximab use in systemic lupus erythematosus pneumonitis and a review of current reports

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Rituximab is a chimeric monoclonal antibody specific for human CD20 that causes selective transient depletion of the CD20+ B‐cell subpopulation. We report the first case of systemic lupus erythematosus (SLE) pneumonitis resistant to conventional treatments that responded well to rituximab and review current reports on the use of rituximab in SLE.
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Keywords: B‐cell depletion; pneumonitis; rituximab; systemic autoimmune disease; systemic lupus erythematosus

Document Type: Research Article

Affiliations: Immunology Department, Institute of Medical and Veterinary Science, Adelaide, South Australia, Australia

Publication date: April 1, 2006

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