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Efficacy of an agonist of α‐MSH, the palmitoyl tetrapeptide‐20, in hair pigmentation

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Hair greying (i.e., canities) is a component of chronological ageing and occurs regardless of gender or ethnicity. Canities is directly linked to the loss of melanin and increase in oxidative stress in the hair follicle and shaft. To promote hair pigmentation and reduce the hair greying process, an agonist of α‐melanocyte‐stimulating hormone (α‐MSH), a biomimetic peptide (palmitoyl tetrapeptide‐20; PTP20) was developed. The aim of this study was to describe the effects of the designed peptide on hair greying.
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Keywords: canities; clinical assay; hair treatment; peptide; α‐MSH/MC1‐R

Document Type: Research Article

Publication date: October 1, 2018

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