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Exploring pathways for sustained melanogenesis in facial melasma: an immunofluorescence study

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The physiopathology of epidermal hypermelanization in melasma is not completely understood. Several cytokines and growth factors are increased in skin with melasma, nevertheless, nor the pathways involved in the increased αMSH expression have been adequately evaluated, nor a model for sustained focal melanogenesis is available.
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Keywords: COX2; melanin; melasma; p38; p53; pigmentation; ultraviolet radiation; α MSH

Document Type: Research Article

Publication date: August 1, 2018

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