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In vitro skin penetration of petrolatum and soybean oil and effects of glyceryl monooleate

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Petrolatum and soybean oil are common ingredients incorporated in topical skin formulations for skin protection and moisturization. However, the stratum corneum (SC) penetration kinetics of these two cosmetic ingredients has not been systematically studied. Glyceryl monooleate (GlyMOle) has been shown to enhance skin penetration of various compounds. It was hypothesized that GlyMOle could enhance skin penetration of petrolatum and soybean oil. This study aimed to examine the in vitro skin penetration of petrolatum and soybean oil in the presence or absence of GlyMOle.
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Keywords: glyceryl monooleate; penetration; petrolatum; skin barrier; skin structure; soybean oil

Document Type: Research Article

Publication date: August 1, 2018

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