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Adenosine‐loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration

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Although dissolving microneedle patches have been widely studied in the cosmetics field, no comparisons have been drawn with the topical applications available for routine use. In this study, two wrinkle‐improving products, adenosine‐loaded dissolving microneedle patches and an adenosine cream, were evaluated for efficacy, with respect to skin wrinkling, dermal density, elasticity, and hydration, and safety in a clinical test on the crow's feet area.
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Keywords: delivery/vectorisation/penetration; dissolving microneedle; safety testing; skin physiology/structure; wrinkle improvement

Document Type: Research Article

Publication date: April 1, 2018

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