Skip to main content
padlock icon - secure page this page is secure

Microneedle‐mediated intradermal delivery of epigallocatechin‐3‐gallate

Buy Article:

$52.00 + tax (Refund Policy)

Epigallocatechin‐3‐gallate (EGCG) is the physiologically most active and abundant flavanol, accounting for 50–80% of green tea catechins. It is an anti‐inflammatory, antioxidant, chemopreventive and skin photoprotective agent. However, light sensitivity and low permeability of EGCG across the stratum corneum due to its high molecular weight as well as strong binding to the lipid bilayers in the skin make it difficult to be used as a key ingredient in cosmetic products. This study aimed to formulate a photostable hydrogel of EGCG with good rheological properties for dermal application and investigate the effect of skin microporation using maltose microneedles on its permeation through dermatomed porcine skin.
No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Keywords: epigallocatechin‐3‐gallate; formulation; microneedles; penetration; rheology; skin barrier

Document Type: Research Article

Publication date: October 1, 2016

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more