Increased level of tumour necrosis factor‐alpha (TNF‐α) on the skin of Japanese obese males: measured by quantitative skin blotting
A state of chronic inflammation, characterized by an increased level of tumour necrosis factor‐alpha (TNF‐α), is often found in the obese population. The negative effects of elevated TNF‐α are not limited to systemic metabolism. It also reportedly affects skin integrity. Recently, the relationship between obesity and skin fragility was reported; however, there has been little insight into how the level of TNF‐α in the skin in situ is related to the severity of obesity. In this study, we aimed to measure the level of TNF‐α on the skin and to find the relationship between obesity and the level of TNF‐α detected on the skin.
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