Skip to main content
padlock icon - secure page this page is secure

Modified Corneosurfametry as a new accelerated high‐throughput ex vivo methodology for predicting cleanser effects towards human skin

Buy Article:

$52.00 + tax (Refund Policy)

Corneosurfametry (CSM) was originally developed as a tool to predict irritation potential of cleansers. In this method, surface skin stripped using cyanoacrylate is contacted with surfactants/products, rinsed and stained with toluidine blue and basic fuschin dyes. The intensity of staining increases with increases in irritation potential of surfactant. Our objective was to modify the CSM technique to achieve better control of the tape stripping process. Another objective was to correlate the modified CSM (MCSM) with a traditional in‐vivo forearm controlled application test (FCAT) for mildness and to explore its utility to assess the state of corneum after a clinical test.
No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Keywords: Mildness; Skin cleansing; claim substantiation in vivo/in vitro; formulation Hair+Body care; moisturisation; polymers/surfactants; sensitive skin/inflammation/allergy

Document Type: Research Article

Publication date: April 1, 2016

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more