Skip to main content
padlock icon - secure page this page is secure

Whitening and antioxidant activities of bornyl acetate and nezukol fractionated from Cryptomeria japonica essential oil

Buy Article:

$52.00 + tax (Refund Policy)


The aim of this study was to investigate the whitening and antioxidant activities of essential oils from Cryptomeria japonica by determining their tyrosinase inhibition, 1,1‐diphenyl‐2‐picrylhydrazyl (DPPH) radical scavenging and superoxide dismutase (SOD)‐like activities.

Essential oils of C.┬ájaponica leaves were extracted with distilled water, and after condensation of volatile constituents, the condensates were extracted with ethyl acetate. Crude essential oils of C.┬ájaponica were divided into six fractions by thin layer chromatography and open column chromatography, and their chemical analysis was performed by GC/MS. Major compounds of fractions were composed of kaurene, bornyl acetate, nezukol, (‐)‐4‐terpineol, δ‐cadinene, α‐terpineol, γ‐eudesmol, α‐eudesmol and elemol.

For tyrosinase inhibitory activity using two substrates, l‐tyrosine and 3,4‐dihydroxyphenylalanine (l‐DOPA), kaurene, bornyl acetate and nezukol were highly effective. In antioxidant activity, (‐)‐4‐terpinenol and δ‐cadinene showed high DPPH radical scavenging activity, and bornyl acetate and nezukol indicated extremely high SOD‐like activity.

Therefore, bornyl acetate and nezukol fractionated from C. japonica essential oil, which showed highly active whitening and antioxidant activities, have potential applications in cosmeceutical materials.
No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Language: French

Document Type: Research Article

Publication date: October 1, 2013

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more