Skip to main content
padlock icon - secure page this page is secure

Non-invasive methods for assessment of dermal UV damage

Buy Article:

$52.00 + tax (Refund Policy)

Repeated exposure to UV radiation can induce cutaneous damage leading to permanent structural degeneration of the dermal extracellular matrix and formation of visible wrinkles. It is not so easy to efface severely UV-damaged skin, because the degenerated abnormal structure of that skin is usually fixed by tight cross-linkings. So, we think that one of the important approaches to the anti-wrinkle skin care is the treatment of photodamaged skin in the early stage. However, it is difficult for most cosmetic users to perceive their dermal UV damage. In the present study, we investigated the possibilities of two non-invasive measurements of skin mechanical properties as convenient biomarkers of degeneration of the extracellular matrix. The condition of the three-dimensional structures of dermal collagen fibres, which depends on the degree of UV damage, correlated with a mechanical parameter measured by the Resiliometer we developed. Accumulation of denatured elastic fibres (elastosis) induced by photoaging correlated with certain mechanical parameters measured by the Cutometer. These findings suggest that dermal structural changes associated with photoaging can be assessed non-invasively using these devices.
No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Document Type: Abstract

Affiliations: 1: Beauty Science R&D Department, Yokohama, Japan 2: Cutaneous Drug Research Laboratories, Yokohama, Japan 3: POLA Chemical Industries, Inc., University of Wales College of Medicine, Cardiff, Wales, U.K. 4: Royal Gwent Hospital, Newport, Wales, Cardiff Biometrics, Ltd, Cardiff, Wales, U.K.

Publication date: December 1, 2004

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more