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Effectiveness of macrogol and talcum base formulations of a new insect repellent N, N‐diethyl phenyl acetamide

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The effectiveness of macrogol and talcum base formulations of a new multi‐insect repellent N, N‐diethyl phenyl acetamide (DEPA) was studied against Aedes aegypti mosquitoes in the laboratory. The efficacy was compared with widely used repellent in India, viz. Dimethylphthalate. Twenty‐five per cent DEPA incorporated macrogol ointment and talcum base formulation offered more than 8 h and 6 h protection, as compared to DMP for 3 h and 1 h 30 min, respectively. The ointment was found to be stable as more than 99% DEPA was recovered by gas liquid chromatography after 6 months of storage at room temperature. The repellent formulations have not shown any gross adverse effect to the skin of albino rabbits.
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Keywords: Aedes aegypti; DEPA; DMP; gas chromatographic analysis; insect repellent; macrogol ointment

Document Type: Research Article

Affiliations: 1: Defence Research & Development Establishment, Gwalior-474002, India 2: *Institute of Nuclear Medicine and Allied Sciences, Probyn Road Delhi, India

Publication date: February 1, 1988

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