Frequency of Factor V Leiden in Juvenile Migraine With Aura
The Leiden mutation was detected in 2 (3.5%) of 57 patients and in 8 (3.7%) of 219 controls. The 2 patients carrying the mutation had no peculiar characteristics as compared with the rest of the migrainous population. In our study, the frequency of the Leiden mutation in patients was not different from that of controls. These data contrast with those collected in the Finnish population and in a group of northwestern Italian adult patients, but agree with results previously reported from The Netherlands.
Document Type: Research Article
Affiliations: 1: From the Department of Pediatrics, University of Ferrara, Italy (Drs. Soriani and Borgna-Pignatti); the 2: Institute of Biology and Genetics, University of Verona, Italy (Ms. Trabetti, Mr. Casartelli, and Dr. Pignatti); and the 3: Department of Neurology, University of Bologna (Dr. Montagna), Italy.
Publication date: November 1, 1998