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Free Content Cannabidiol as a new treatment for drug‐resistant epilepsy in tuberous sclerosis complex

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Tuberous sclerosis complex (TSC) is an autosomal‐dominant genetic disorder with highly variable expression. The most common neurologic manifestation of TSC is epilepsy, which affects approximately 85% of patients, 63% of whom develop treatment‐resistant epilepsy. Herein, we evaluate the efficacy, safety, and tolerability of cannabidiol (CBD), a nonpsychoactive compound derived from the marijuana plant, as an adjunct to current antiepileptic drugs in patients with refractory seizures in the setting of TSC.
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Keywords: Cannabidiol; Efficacy; Seizures; Tolerability; Tuberous sclerosis complex

Document Type: Research Article

Publication date: 01 October 2016

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