Skip to main content
padlock icon - secure page this page is secure

Dietary mushroom (Pleurotus ostreatus) ameliorates atherogenic lipid in hypercholesterolaemic rats

Buy Article:

$52.00 + tax (Refund Policy)


1. The effects of edible oyster mushroom Pleurotus ostreatus on plasma and liver lipid profiles and on the plasma total anti-oxidant status were estimated in hyper- and normocholesterolaemic Long Evans rats.

2. The feeding of 5% powder of the fruiting bodies of P. ostreatus mushrooms to hypercholesterolaemic rats reduced their plasma total cholesterol by approximately 28%, low-density lipoprotein–cholesterol by approximately 55%, triglyceride by approximately 34%, non-esterified fatty acid by approximately 30% and total liver cholesterol levels by > 34%, with a concurrent increase in plasma high-density lipoprotein–cholesterol concentration of > 21%. However, these effects were not observed in mushroom-fed normocholesterolaemic rats.

3. Mushroom feeding significantly increased plasma fatty acid unsaturation in both normo- and hypercholesterolaemic rats.

4. Plasma total anti-oxidant status, as estimated by the oxidation of 2,2′-azino-bis-[3-ethylbenz-thiazoline-6-sulphonic-acid], was significantly decreased in mushroom-fed hypercholesterolaemic rats, concomitant with a decrease in plasma total cholesterol.

5. The present study suggests that 5% P. ostreatus supplementation provides health benefits, at least partially, by acting on the atherogenic lipid profile in the hypercholesterolaemic condition.
No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Keywords: Pleurotus ostreatus; atherogenic lipid profile; hypercholesterolaemia; total anti-oxidant status; unsaturation index

Document Type: Research Article

Affiliations: 1: Department of Physiology, Shimane Medical University, Shimane, Japan, Departments of 2: Department of Biochemistry & Molecular Biology, University of Dhaka, 3: Botany and 4: International Center for Diarrheal Diseases and Research and 5: Center for Scientific and Industrial Research, Dhaka, Bangladesh 6: Pharmacy, Jahangirnagar University,

Publication date: July 1, 2003

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more