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Odorant inhalation affects skin barrier homeostasis in mice and humans

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Previous studies have suggested that psychological stress delays cutaneous barrier recovery following acute barrier disruption, and that sedative drugs block this delay. A sedative effect of some odorants has been reported. In the present study, we demonstrate that odorant inhalation affects cutaneous barrier homeostasis in both mice and humans. Odorants with a sedative effect prevented the delay of skin barrier recovery induced by stress after acute barrier disruption. Other odorants did not show this effect.
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Keywords: homeostasis; odorant inhalations; skin barrier

Document Type: Research Article

Affiliations: Shiseido Research Center 2, 2-12-1 Fukuura, Kanazawa-ku, Yokohama 236-8643, Japan

Publication date: May 1, 2000

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