Skip to main content
padlock icon - secure page this page is secure

Ivermectin alone or in combination with benzyl benzoate in the treatment of human immunodeficiency virus-associated scabies

Buy Article:

$52.00 + tax (Refund Policy)

In order to establish a safe and reliable treatment for human immunodeficiency virus (HIV)-associated scabies, we have treated 60 episodes of scabies in this setting, occurring in 39 patients, with one of the following regimens: (i) topical treatment with benzyl benzoate solution; (ii) single-dose oral treatment with ivermectin alone; and (iii) combination therapy with benzyl benzoate solution and oral ivermectin, employing the same regimens as single-agent therapy. Patients were stratified according to the severity score of the disease and the outcome (eradication, relapse, failure). We found that both benzyl benzoate and ivermectin alone were quite effective in mild to moderate scabies, but they were both associated with an unacceptable rate of relapse and failure in severe or crusted scabies. In contrast, combined treatment produced an optimal rate of success, without significant treatment-related side-effects. Therefore, we consider that combination treatment with benzyl benzoate solution and oral ivermectin is preferable to single-agent therapy in crusted scabies occurring in HIV/acquired immune deficiency syndrome patients.
No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Keywords: acquired immune deficiency syndrome; human immunodeficiency virus; ivermectin; scabies; topical treatments

Document Type: Research Article

Affiliations: 1: Unit of Infectious Diseases, Azienda Ospedaliera di Piacenza, Via Taverna 49, I-29100 Piacenza, Italy 2: Clinic of Infectious and Tropical Diseases, Spedali Civili Brescia, Brescia, Italy

Publication date: May 1, 2000

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more