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CD56 expression in a case of primary cutaneous CD30+ anaplastic large cell lymphoma

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We describe clinicopathological features of an unusual case of CD30+/CD56+ T-cell lymphoma in a 58-year-old Korean man who presented with disseminated nodules, papules and hyperpigmented patches. Coexpression of CD30 and CD56 in T-cell lymphoma is very rare. Our patient did not respond to an intensive chemotherapy regimen, in contrast to the previously reported cases of primary cutaneous CD30+ anaplastic large cell lymphoma. Coexpression of CD56 might therefore identify a subset of CD30+ lymphomas with more aggressive features.
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Keywords: CD30; CD56; T-cell lymphoma; anaplastic large cell lymphoma

Document Type: Research Article

Affiliations: 1: Departments of Dermatology and 2: Pathology, Asan Medical Center, College of Medicine, University of Ulsan, 388-1 Poongnap-Dong, Songpa-Gu, Seoul 138-736, Korea

Publication date: April 1, 2000

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