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The title compound, C19H22NClO3, was synthesized by an intramolecular condensation reaction of N-[2-hydroxy-2-(methoxy­phenyl)­ethyl]-2-(2-chloro-3,4-di­methoxy­phenyl)­ethyl­amine in tri­fluoro­acetic acid with 36 N H2SO4 at room temperature and obtained in 69% yield. The crystal structure determined by X-ray diffraction shows normal bond lengths and angles. The seven-membered ring adopts a half-chair conformation.
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Document Type: Research Article

Publication date: December 1, 2004

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