A bromine analogue of picoplatin: a new substance from the group of platinum‐based chemotherapeutics
A new substance, cis‐amminedibromido(2‐methylpyridine‐κN)platinum(II), cis‐[PtBr2(C6H7N)(NH3)], which is a potential platinum‐based antineoplastic agent for the treatment of patients with solid tumors, has been synthesized and structurally characterized. There is one molecule in the asymmetric unit and molecules are linked via two symmetry‐independent N—H...Br hydrogen bonds into zigzag chains running parallel to the c axis. C—H...Br hydrogen bonds crosslink these chains to give a layer parallel to (010). N—H...Br hydrogen bonds and π–π stacking interactions between pairs of pyridine rings stack the layers along b.
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Document Type: Research Article
Publication date: April 15, 2013