Skip to main content
padlock icon - secure page this page is secure

A cell wall preparation of Enterococcus faecalis strain EC-12 stimulates β-defensin expression in newly hatched broiler chicks

Buy Article:

$52.00 + tax (Refund Policy)

ABSTRACT

In our previous study, a cell wall preparation of Enterococcus faecalis strain EC-12 (EC-12) prevented the colonization of vancomycin-resistant enterococci (VRE) in newly hatched broiler chicks. Relatively early prevention against VRE colonization by EC-12 administration may be related to the enhanced innate immune system. In this study we examined the effect of EC-12 on the kinetics of immunoglobulin A (IgA) concentration in the cecal digesta of chicks from 1 day to 14 days old to evaluate humoral immunity. We also examined the effect of EC-12 on β-defensin mRNA expression and lysozyme production. The IgA concentration in the cecal digesta showed a decline in chicks from 2 to 8 days old and then a recovery up to when they were 14 days old. The concentration tended to be higher in EC-12-administered chicks than in control chicks at 14 days old. EC-12 administration did not stimulate the lysozyme activities in the alimentary tract. However, β-defensin mRNA expression in the tongue and the bursa of Fabricius was higher in chicks administered EC-12 than in the control chicks at 5 days old. These results indicate that β-defensin may be one of the major defense mechanisms inhibiting VRE colonization in young chicks.
No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Keywords: Enterococcus faecalis EC-12; immunoglobulin A; lysozyme; vancomycin-resistant Enterococci; β-defensin

Document Type: Research Article

Affiliations: 1: Laboratory of Animal Science, Kyoto Prefectural University, Sakyo, Kyoto, 2: Combi, Saitama, Japan

Publication date: February 1, 2007

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more