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Randomized, blinded study to assess the effect of povidone‐iodine on the groin wound of patients undergoing primary varicose vein surgery

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The aim of this study was to assess the effect of povidone‐iodine on the groin wounds of patients undergoing primary varicose vein surgery.

This is a prospective, randomized, blinded, controlled study on patients undergoing primary saphenofemoral ligation. Patients were randomized to a povidone‐iodine (Betadine; Pfizer, West Ryde, Australia)‐soaked surgical gauze placed in the open wound or a saline‐soaked gauze placed in the wound. Patients were then followed up weekly for 6 weeks to observe for signs of wound infection.

Sixty‐eight legs in 49 patients were recruited. Thirty‐seven groin wounds were randomized to saline and 32 to Betadine. There was a reduced incidence of groin wound infections in those randomized to Betadine (3 versus 1), but this was not statistically significant (P = 0.4).

Although there may be a trend towards a lower wound infection rate when povidone‐iodine is use in surgical wounds, this is not significant for varicose vein surgery.
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Document Type: Research Article

Publication date: November 1, 2013

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