Randomized, blinded study to assess the effect of povidone‐iodine on the groin wound of patients undergoing primary varicose vein surgery
The aim of this study was to assess the effect of povidone‐iodine on the groin wounds of patients undergoing primary varicose vein surgery.
This is a prospective, randomized, blinded, controlled study on patients undergoing primary saphenofemoral ligation. Patients were randomized to a povidone‐iodine (Betadine; Pfizer, West Ryde, Australia)‐soaked surgical gauze placed in the open wound or a saline‐soaked gauze placed in the wound. Patients were then followed up weekly for 6 weeks to observe for signs of wound infection.
Sixty‐eight legs in 49 patients were recruited. Thirty‐seven groin wounds were randomized to saline and 32 to Betadine. There was a reduced incidence of groin wound infections in those randomized to Betadine (3 versus 1), but this was not statistically significant (P = 0.4).
Although there may be a trend towards a lower wound infection rate when povidone‐iodine is use in surgical wounds, this is not significant for varicose vein surgery.
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Document Type: Research Article
Publication date: November 1, 2013