Celecoxib‐Induced Change in Atrial Electrophysiologic Substrate in Arthritis Patients
Cyclooxygenase‐2 inhibitors, the newest class of nonsteroidal antiinflammatories, pose an increased risk of adverse cardiovascular events, in particular atrial fibrillation (AF). We hypothesized that the COX‐2 inhibitor celecoxib alters atrial electrophysiology, and thus promotes the development of AF.
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