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Prenatal unhealthy diet, insulin‐like growth factor 2 gene (IGF2) methylation, and attention deficit hyperactivity disorder symptoms in youth with early‐onset conduct problems

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Conduct problems (CP) and attention deficit hyperactivity disorder (ADHD) are often comorbid and have each been linked to ‘unhealthy diet’. Early‐life dietĀ also associates with DNA methylation of the insulin‐like growth factor 2 gene (IGF2), involved in fetal and neural development. We investigated the degree to which prenatal high‐fat and ‐sugar diet might relate to ADHD symptoms via IGF2 DNA methylation for early‐onset persistent (EOP) versus low CP youth. Read the Commentary on this article at doi: 10.1111/jcpp.12649
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Keywords: Avon Longitudinal Study of Parents and Children; DNA methylation; IGF2; attention deficit hyperactivity disorder; conduct problems; diet

Document Type: Original Article

Publication date: January 1, 2017

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