Skip to main content
padlock icon - secure page this page is secure

Emotional lability in children and adolescents with attention deficit/hyperactivity disorder (ADHD): clinical correlates and familial prevalence

Buy Article:

$59.00 + tax (Refund Policy)


The goal of this study was to investigate the occurrence, severity and clinical correlates of emotional lability (EL) in children with attention deficit/hyperactivity disorder (ADHD), and to examine factors contributing to EL and familiality of EL in youth with ADHD. Methods: 

One thousand, one hundred and eighty-six children with ADHD combined type and 1827 siblings (aged 6–18 years) were assessed for symptoms of EL, ADHD, associated psychopathology and comorbid psychiatric disorders with a structured diagnostic interview (PACS) as well as parent and teacher ratings of psychopathology (SDQ; CPRS-R:L; CTRS-R:L). Analyses of variance, regression analyses, χ2-tests or loglinear models were applied. Results: 

Mean age and gender-standardized ratings of EL in children with ADHD were >1.5 SD above the mean in normative samples. Severe EL (>75th percentile) was associated with more severe ADHD core symptoms, primarily hyperactive-impulsive symptoms, and more comorbid oppositional defiant, affective and substance use disorders. Age, hyperactive-impulsive, oppositional, and emotional symptoms accounted for 30% of EL variance; hyperactive-impulsive symptoms did not account for EL variance when coexisting oppositional and emotional problems were taken into account, but oppositional symptoms explained 12% of EL variance specifically. Severity of EL in probands increased the severity of EL in siblings, but not the prevalence rates of ADHD or ODD. EL and ADHD does not co-segregate within families. Conclusion: 

EL is a frequent clinical problem in children with ADHD. It is associated with increased severity of ADHD core symptoms, particularly hyperactivity-impulsivity, and more symptoms of comorbid psychopathology, primarily symptoms of oppositional defiant disorder (ODD), but also affective symptoms, and substance abuse. EL in ADHD seems to be more closely related to ODD than to ADHD core symptoms, and is only partly explainable by the severity of ADHD core symptoms and associated psychopathology. Although EL symptoms are transmitted within families, EL in children with ADHD does not increase the risk of ADHD and ODD in their siblings.
No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Keywords: Attention deficit/hyperactivity disorder; affective lability; emotional dysregulation; emotional lability

Document Type: Research Article

Affiliations: 1: Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany 2: MRC Social Genetic Developmental and Psychiatry Centre, Institute of Psychiatry, London, UK 3: Department of Psychiatry, Donders Institute for Brain, Cognition and Behavior, Centre for Neuroscience, Radboud University Nijmegen Medical Center, Nijmegen, the Netherlands 4: Department of Child & Adolescent Psychiatry, Central Institute of Mental Health, Mannheim, Germany 5: Department of Biostatistics, Central Institute of Mental Health, Mannheim, Germany 6: Clinical Neuropsychology, Vrije Universiteit, Amsterdam, the Netherlands 7: Trinity Centre for Health Sciences, St James’s Hospital, Dublin, Ireland 8: S. Herzog Memorial Hospital, Jerusalem, Israel 9: Department of Developmental and Educational Psychology, University of Valencia, Valencia, Spain 10: University Clinic for Child and Adolescent Psychiatry and Psychotherapy, Essen, Germany 11: Departments of Experimental Clinical Health Psychology, Ghent University, Belgium 12: Child and Adolescent Psychiatry, University of Goettingen, Germany 13: Departments of Psychiatry and Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, NY, USA

Publication date: August 1, 2010

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more