Skip to main content
padlock icon - secure page this page is secure

The prodrome of autism: early behavioral and biological signs, regression, peri- and post-natal development and genetics

Buy Article:

$59.00 + tax (Refund Policy)

Autism is one of the most heritable neurodevelopmental conditions and has an early onset, with symptoms being required to be present in the first 3 years of life in order to meet criteria for the ‘core’ disorder in the classification systems. As such, the focus on identifying a prodrome over the past 20 years has been on pre-clinical signs or indicators that will be present very early in life, certainly in infancy. A number of novel lines of investigation have been used to this end, including retrospective coding of home videos, prospective population screening and ‘high risk’ sibling studies; as well as the investigation of pre- and peri-natal, brain developmental and other biological factors. While no single prodromal sign is expected to be present in all cases, a picture is emerging of indicative prodromal signs in infancy and initial studies are being undertaken to attempt to ameliorate early presentation and even ‘prevent’ emergence of the full syndrome.
No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Keywords: Autism spectrum disorders; brain development; diagnosis; early markers; genetics; perinatal development; siblings

Document Type: Research Article

Affiliations: 1: Department of Psychology and School of Education, The Hebrew University of Jerusalem, Israel 2: Centre for Research in Autism and Education, Institute of Education, London, UK

Publication date: April 1, 2010

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more