Skip to main content
padlock icon - secure page this page is secure

Crystallization and preliminary crystallographic characterization of three peptidic inhibitors in complex with α‐thrombin

Buy Article:

$52.00 + tax (Refund Policy)

The serine protease thrombin plays a major role in thrombosis and haemostasis. This has driven interest in thrombin inhibitors as potential antithrombotic drugs. Here, the crystallization and preliminary crystallographic analysis of human α‐thrombin in complex with three noncovalent peptide inhibitors of the general sequence d‐Phe‐Pro‐d‐Arg‐P1′‐CONH2 are reported. The crystals belonged to the orthorhombic space group P212121 and diffracted to beyond 1.3 Å resolution.
No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Keywords: blood coagulation; noncovalent; peptide inhibitors; thrombin

Document Type: Research Article

Publication date: January 1, 2011

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more