Skip to main content
padlock icon - secure page this page is secure

Crystallization and preliminary X‐ray analysis of the PIN domain of human EST1A

Buy Article:

$52.00 + tax (Refund Policy)

Human EST1A (ever shorter telomeres 1A) is associated with most or all active telomerase in cell extracts and is involved either directly or indirectly in telomere elongation and telomere capping. The C‐terminal region of EST1A contains the PIN (PilT N‐terminus) domain, a putative nuclease domain. The PIN domain of human EST1A was expressed, purified and crystallized by the sitting‐drop vapour‐diffusion method. The crystals belonged to space group C2, with unit‐cell parameters a = 107.3, b = 51.6, c = 100.5 Å, β = 119.3°, and diffracted X‐rays to 1.8 Å resolution. The asymmetric unit contained two molecules of the PIN domain and the solvent content was 57%.
No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Keywords: EST1A; PIN domains

Document Type: Research Article

Publication date: July 1, 2006

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more