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Lactone, 14. Mitt.: Synthese lactonverbrückter 1,1‐Diarylethylamine

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Umsetzung der 5,5‐Diaryl‐2(5H)‐furanone 4a–d mit überschüssigen Aminen liefert Aminoamide 5a–k, die durch Hydrolyse und Ringschluß in die gewünschten 4‐Amino‐5,5‐diaryl‐4,5‐dihydro‐2(3H)‐furanone 6a–k überführt werden. Lactones, XIV: Synthesis of Lactone‐Bridged 1,1‐Diarylethanamines Reaction of the 5,5‐diaryl‐2(5H)‐furanones 4a–d with excess of amines gives the aminoamides 5a–k, which are transformed into the desired 4‐amino‐5,5‐diaryl‐4,5‐dihydro‐2(3H)‐furanones 6a–k by hydrolysis and ring closure.
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Document Type: Research Article

Affiliations: Institut für Pharmazeutische Chemie der Universität Hamburg, Bundesstr. 45, D-2000 Hamburg 13

Publication date: October 1, 1987

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