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Optisch aktive Tetrahydro‐diazixanopurine

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Optisch aktive Tetrahydro‐diazixanopurine können auf zwei Wegen aus Vorstufen, die über eine Racematspaltung gewonnen worden sind, hergestellt werden. Untersuchungen zur Konfiguration weisen auf eine R‐Konfiguration des Diazixanopurins (+)‐4 hin. Optically Active Tetrahydro‐diazixanopurines After resolution of racemic 8‐chloro‐7‐(3‐hydroxybutyl)theophylline, optically active diazixanopurines are obtained in two ways. Several methods were applied to determine the absolute configurations of the compounds described. The diazixanopurine (+)‐4, has R configuration.
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Document Type: Research Article

Affiliations: Pharmazeutisches Institut der Universität Kiel, Gutenbergstr. 76–78, D-2300 Kiel

Publication date: 01 October 1987

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