Skip to main content
padlock icon - secure page this page is secure

Endobronchial Infection in Cystic Fibrosis

Buy Article:

$52.00 + tax (Refund Policy)

In symptomatic patients with cystic fibrosis, the recovery of bacteria in an inflammatory exudate from the lower respiratory tract is strong evidence of endobronchitis. It is not known when this chronic infection begins, the etiologic agents during infancy or the mechanism of evolution from Haemophilus influenzae and Staphylococcus aureus to Pseudomonas aeruginosa. Antibiotic administration to “suppress” the infection in relatively well patients is an unproven benefit. During an exacerbation of bronchitis, administration of appropriate antibiotics decreases sputum bacterial density and is accompanied by decreased amounts of indicators of inflammation in sputum: pulmonary function improves, particularly that reflecting medium to small airway status. In the future aggressive diagnostic procedures will be followed by therapeutic and prophylactic antibiotic administration conducted in a manner to minimize emergence of antibiotic‐resistant bacteria. Adjunctive therapy, to minimize those aspects of the host response which inflict lung damage, will become standard.
No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Keywords: bronchitis; cystic fibrosis

Document Type: Research Article

Affiliations: From the Department of Pediatrics, Division of Infectious Disease, Pulmonary Medicine, and the Department of Pathology, Children's Hospital and Medical Center University of Washington, Seattle, WA 98105, USA

Publication date: November 1, 1989

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more