@article {Jost:2001:0929-8665:423,
title = "In Vitro Degradation Of beta-Amyloid[25-35] Peptide",
journal = "Protein and Peptide Letters",
parent_itemid = "infobike://ben/ppl",
publishercode ="ben",
year = "2001",
volume = "8",
number = "6",
publication date ="2001-12-01T00:00:00",
pages = "423-428",
itemtype = "ARTICLE",
issn = "0929-8665",
url = "https://www.ingentaconnect.com/content/ben/ppl/2001/00000008/00000006/art00001",
doi = "doi:10.2174/0929866013409076",
keyword = "Alzheimer disease, AMYLOID PEPTIDE",
author = "Jost, K. and Varga, J. and Pence, B. and Zarandi, M.",
abstract = "Some amyloid-derived peptides show their toxic effects only after a long aging period performed several days at pH 7.4 and 37 C for cluster formation. Our experiments show that long aging of beta-amyloid[25-35] under physiological conditions results in peptide bond cleavage between Asn27 and Lys28. Relatively short incubation time (24 hours) and absence of Ca2+ ions prevent peptide cleavage and results in good aggregation of beta-amyloids.",
}