Skip to main content
padlock icon - secure page this page is secure

Natural Products as a Source of CNS-Active Agents

Buy Article:

$63.00 + tax (Refund Policy)

Disease and disorders of the central nervous system (CNS) are some of the most common ailments afflicting mankind, and it has been estimated that 32% of the population of the USA suffers from a disorder of the brain once in a lifetime, and 15% of the population over 18 suffer a mental disorder at least monthly. The use of natural products as psychotropic agents to alleviate mental disorders, or to create altered mental states, probably dates back to the dawn of time, when the first trial-and-error experiments by shamans or other experimenters led to the discovery of the effect of certain plant extracts on the mind. It is thus significant that the first alkaloid to be purified from a plant was the psychoactive analgesic morphine.

Although there is extensive literature on the use of plants and plant extracts as hallucinogenic agents, the search for natural products for therapeutic psychotropic purposes is much less well-developed than, for example, the search for anticancer agents. Nevertheless, there are enough examples of the successful search for useful naturally-occurring psychotropic agents to ensure that a continued search is likely to be productive.

This review will summarize results in the discovery of CNS-active natural products, with an emphasis on compounds that may be useful for therapeutic purposes.
No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Keywords: CNS-Active Agents; anticancer agents

Document Type: Review Article

Affiliations: Department of Chemistry, Virginia Polytechnic Institute and State University, M / C 0212, Blacksburg VA 24061-0212 USA.

Publication date: 01 April 2004

More about this publication?
  • Mini-Reviews in Organic Chemistry publishes original reviews on all areas of organic chemistry including synthesis, bioorganic, medicinal, natural products, organometallic, supramolecular, molecular recognition, and physical organic chemistry. The emphasis will be on publishing quality papers very rapidly. Mini-reviews will be processed rapidly by taking full advantage of Internet technology for both the submission and review of manuscripts.

    The journal is essential reading to all organic chemists in both academia and industry.
  • Editorial Board
  • Information for Authors
  • Subscribe to this Title
  • Ingenta Connect is not responsible for the content or availability of external websites
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more