Medicinal Chemistry

Editorial [Hot Topics: New Trends in Micro- and Nano-systems Development for Pharmaceutical Actives Release]
pp. 515-515(1)
Author: Martin-Banderas, Lucia

Synthesis of a Biodegradable Magnetic Nanomedicine Based on the Antitumor Molecule Tegafur
pp. 516-523(8)
Authors: L. Arias, Jose; Saez-Fernandez, Eva; Lopez-Viota, Margarita; A. Biedma-Ortiz, Rafael; Adolfina Ruiz, Mª

Monodisperse Nanoparticles from Self-Assembling Amphiphilic Cyclodextrins: Modulable Tools for the Encapsulation and Controlled Release of Pharmaceuticals
pp. 524-532(9)
Authors: Mendez-Ardoy, Alejandro; Gomez-Garcia, Marta; Geze, Annabelle; Putaux, Jean-Luc; Wouessidjewe, Denis; Ortiz Mellet, Carmen; Defaye, Jacques; M. Garcia Fernandez, Jose; M. Benito, Juan

Use of Flow Focusing® Technology to Produce Tobramycin-Loaded Plga Microparticles for Pulmonary Drug Delivery
pp. 533-540(8)
Authors: Martin-Banderas, Lucia; Angeles Holgado, Maria; Alvarez-Fuentes, Josefa; Fernandez- Arevalo, Mercedes

Preparation, Chemical and Electrical Characterizations of Lipid Nanoparticles Loaded with Dihydroxybenzophenone
pp. 541-548(8)
Authors: Jesus, Hierrezuelo; Juana, Benavente; Juan Manuel, Lopez–Romero; de Yuso Maria del Valle, Martinez; Enrique, Rodriguez–Castellon

Editorial [Hot Topic: Calcium Metabolism and Treatment of Hypercalcemia]
pp. 549-550(2)
Author: Lumachi, Franco

Diagnosis of Alterations of Serum Calcium Metabolism
pp. 551-555(5)
Authors: Lumachi, Franco; Cappelletti, Piero; Tozzoli, Renato; M.M. Basso, Stafano; Luisetto, Giovanni; Camozzi, Valentina

Treatment of Chronic Hypercalcemia
pp. 556-563(8)
Authors: Camozzi, Valentina; Luisetto, Giovanni; M.M. Basso, Stefano; Cappelletti, Piero; Tozzoli, Renato; Lumachi, Franco

Treatment of Acute Hypercalcemia
pp. 564-568(5)
Authors: M.M. Basso, Stafano; Lumachi, Franco; Nascimben, Fabiana; Luisetto, Giovanni; Camozzi, Valentina

New Adamantane Derivatives with Sigma Affinity and Antiproliferative Activity
pp. 569-586(18)
Authors: Riganas, Stefanos; Papanastasiou, Ioannis; B. Foscolos, George; Tsotinis, Andrew; Dimas, Kostas; N. Kourafalos, Vassilios; Eleutheriades, Andreas; I. Moutsos, Vassilios; Khan, Humaira; Margarita, Prassa; Georgakopoulou, Stavroula; Zaniou, Angeliki; Theodoropoulou, Maria; Mantelas, Athanasios; Pondiki, Stavroula; Vamvakides, Alexandre

Design, Synthesis and Antiproliferative Activity of 2-Acetamidothiazole-5- carboxamide Derivatives
pp. 587-594(8)
Authors: Liu, Wukun; Zhou, Jinpei; Zheng, Yu; Qi, Fan; Zhang, Huibin; Qian, Hai; Wang, Jing; Cheng, Yanhua; Gust, Ronald

Synthesis of 3-(2, 8, 9-trioxa-5-aza-1-germatricyclo [3.3.3.0] Undecane-1- yl)-3-(4-hydroxyl-3-methoxyphenyl)-propionic Acid and its Inhibitory Effect on the Cervical Tumor U14 in vitro and in vivo
pp. 595-598(4)
Authors: Ye, Lianbao; Ou, Xiaomin; Peng, Xuedong; Luo, Yan

A QSAR Analysis of 2-phenoxy-N-substituted Acetamide Analogues as Hypoxia-Inducible Factor-1(HIF-1) Inhibitors: A Rational Approach to Anticancer Drug Design
pp. 599-614(16)
Authors: N. Noolvi, Malleshappa; M. Patel, Harun; Kamboj, Sarita

Differences in Vanadocene Dichloride and Cisplatin Effect on MOLT-4 Leukemia and Human Peripheral Blood Mononuclear Cells
pp. 615-621(7)
Authors: Havelek, Radim; Siman, Pavel; Cmielova, Jana; Stoklasova, Alena; Vavrova, Jirina; Vinklarek, Jaromir; Knizek, Jiri; Rezacova, Martina

The Preformulation Stability Studies of a Proline Prodrug of Methotrexate
pp. 622-628(7)
Authors: Stephenson, Ann; Wu, Zhiqian; Yuan, Xudong

Synthesis, In Vitro and In Silico NS5B Polymerase Inhibitory Activity of Benzimidazole Derivatives
pp. 629-635(7)
Authors: M. Patil, Vaishali; K. R., Gurukumar; Chudayeu, Maksim; Prakash Gupta, Satya; Samanta, Subeer; Masand, Neeraj; Kaushik-Basu, Neerja

Structural Insight for Imidazopyridazines as Malarial Kinase PfPK7 Inhibitors Using QSAR Techniques
pp. 636-648(13)
Authors: K. Sahu, Nitendra; V. Kohli, D.

A QSAR Study on a Series of Pyrrole Derivatives Acting as Lymphocyte- Specific Kinase (Lck) Inhibitors
pp. 649-655(7)
Authors: Anwer, Zaihra; P. Gupta, Satya

A QSAR Study on Novel Series of Carbonic Anhydrase Inhibitors hCA IX—Tumor-Associated (Hypoxia)
pp. 656-672(17)
Author: Singh, Shalini

Computational Approaches to Improve Aggrecanase-1 Inhibitory Activity of (4-keto) Phenoxy) Methyl Biphenyl-4-sulfonamide: Group Based QSAR and Docking Studies
pp. 673-682(10)
Authors: Malliappan Sivakumar, Ponnurengam; Vignesh Selvaraj, Naga; Ramesh, G.; Mohanapriya, J.; Prabhawathi, Veluchamy; Doble, Mukesh

Synthesis and Biological Evaluation of Naloxone and Naltrexone-Derived Hybrid Opioids
pp. 683-689(7)
Authors: E. Nassim, Bahman; Wang, Ming-Lei

In vitro Synergy Testing of Anidulafungin with Fluconazole, Tioconazole, 5-Flucytosine and Amphotericin B against some Candida spp.
pp. 690-698(9)
Authors: Rosato, Antonio; Piarulli, Monica; Immacolata Pia Schiavone, Brigida; Teresa Montagna, Maria; Caggiano, Giuseppina; Muraglia, Marilena; Carone, Addolorata; Franchini, Carlo; Corbo, Filomena

Synthesis of Novel 4-Aryl-1,2,3,4-tetrahydroisoquinolines as Probes for Dopamine Receptor Ligands
pp. 699-704(6)
Authors: Giorgioni, Gianfabio; Ambrosini, Dario; Filippo Palmieri, Giovanni; Costa, Barbara; Di Stefano, Antonio; Martini, Claudia

Acylhydrazide Schiff Bases: DPPH Radical and Superoxide Anion Scavengers
pp. 705-710(6)
Authors: Mohammed Khan, Khalid; Taha, Muhammad; Naz, Farzana; Siddiqui, Salman; Ali, Sajjad; Rahim, Fazal; Perveen, Shahnaz; Iqbal Choudhary, M.

Synthesis and Biological Evaluation of a Series of 6,7-dimethoxy-1-(3,4- dimethoxybenzyl)-2-substituted Tetrahydroisoquinoline Derivatives
pp. 711-716(6)
Authors: Zou, Zhi-hong; Lan, Xiao-bu; Tang, Chun-lei; Zhu, Xiao-yun; Liu, Bao-min; Qian, Hai; Huang, Wen-long; Li, Yun-man

A QSAR Study of Biphenyl Analogues of 2-Nitroimidazo-[2, 1-b] [1, 3] - oxazines as Antitubercular Agents Using Genetic Function Approximation
pp. 717-726(10)
Authors: Ray, Supratim; Pratim Roy, Partha

Synthesis and 188Re Radiolabelling of Dendrimer Polyamide Amine (PAMAM) Folic Acid Conjugate
pp. 727-731(5)
Authors: Cui, Wei; Zhang, Yuanqing; Xu, Xiaoping; Shen, Yu-Mei

In Vitro Antibacterial and Antifungal Activity of Salicylanilide Pyrazine-2- carboxylates
pp. 732-741(10)
Authors: Kratky, Martin; Vinsova, Jarmila; Buchta, Vladimir

Design, Synthesis and Multidrug Resistance Reversal Activity Evaluation of 8-Oxocoptisine Derivatives
pp. 742-748(7)
Authors: Bo Wu, Jian; Lei, Fan; Juan Cui, Xiang; He, Yun; Hai, Li; Zhang, Juan; Wu, Yong

Serum Specific Vasopressin-Degrading Activity is Related to Blood Total Cholesterol Levels in Men but not in Women
pp. 749-752(4)
Authors: Maria Jesus, Ramirez-Exposito; Marcelina, Arrazola; Maria Pilar, Carrera-Gonzalez; de Saavedra Jose Manuel, Arias; Rafael, Sanchez-Agesta; Maria Dolores, Mayas; Jose Manuel, Martinez-Martos

Prodrug Strategies in Ocular Drug Delivery
pp. 753-768(16)
Authors: Barot, Megha; Bagui, Mahuya; R. Gokulgandhi, Mitan; K. Mitra, Ashim