22% Co/CeO2-ZrO2-catalyzed Synthesis of 1, 2, 3, 4-tetrahydro-2- pyrimidinones and -thiones
Three-component condensation reaction of an aldehyde with β-ketoester and urea or thiourea in acetonitrile to afford the dihydropyrimidinones and thions (DHPMs) in the presence of 22% Co/CeO2-ZrO2 nano fine particle as a novel, reusable and green catalyst is reported. Utilizing of 22% Co/CeO2-ZrO2 nano fine particle catalyst also offers a cleaner process in that it can be reused and will not bring additional pollutants into the “environment” that is agreeable green chemistry point of view.
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Document Type: Research Article
Publication date: October 1, 2012
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