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Letters in Drug Design & Discovery publishes original letters on all areas of rational drug design and discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, and structure-activity relationships. The emphasis will be on publishing quality papers very rapidly. Letters will be processed rapidly by taking full advantage of Internet technology for both the submission and review of manuscripts. The journal is essential reading to all pharmaceutical scientists involved in research in drug design and discovery.

Publisher: Bentham Science Publishers

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Volume 13, Number 5, 2016

Articles

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Design, Synthesis and ex vivo Study of the Vasorelaxant Activity Induced by Isosteric Derivatives of Dihydropyridines (NH→O)
pp. 353-359(7)
Authors: Rendón-Vallejo, Priscila; Estrada-Soto, Samuel; A. Vázquez, Miguel; Hernández- Borja, Fernando; Villalobos-Molina, Rafael; Ibarra-Barajas, Maximiliano

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Flexibility in the Molecular Design of Acetylcholinesterase Reactivators: Probing Representative Conformations by Chemometric Techniques and Docking/QM Calculations
pp. 360-371(12)
Authors: E.A. de Lima, Willian; F. Pereira, Ander; A. de Castro, Alexandre; F.F. da Cunha, Elaine; C. Ramalho, Teodorico

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TRISOXIME – a Bulky Trisquaternary Reactivator of Acetylcholinesterase
pp. 372-375(4)
Authors: Kuca, Kamil; Musilek, Kamil; Jun, Daniel

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CoMFA/CoMSIA and Molecular Docking Studies of Novel Matrix Metalloproteinase- 2 Inhibitors Based on L-tyrosine Scaffold
pp. 376-386(11)
Authors: Jun-Zhang; Wang, Xue-Jiao; Dong, Zhen-Ke; Wang, Shu-Qing; Xu, Wei-Ren; Fu, Jing-Wei; Cheng, Xian- Chao; Wang, Run-Ling

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Synthesis, Neuro-protection and Anti-cancer Activities of Simple Isatin Mannich and Schiff Bases
pp. 395-400(6)
Authors: Chen, Gang; Ning, Yang; Zhao, Wei; Zhang, Yanqiu; Zhang, Yu; Hao, Xiaojiang; Wang, Ye; Mu, Shuzhen

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Modified Hummel-Dreyer Method and Molecular Modeling Studies Identified Nicotinic Acid Analogues as Carbonic Anhydrase III Ligands
pp. 401-410(10)
Authors: Jarrar, Nada; Alzweiri, Muhammed; Al-Hiari, Yusuf; Farah, Shrouq; A. Khanfar, Mohammad

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Antinociceptive Activities of Some 4,5-Dihydro-1H-Pyrazole Derivatives: Involvement of Central and Peripheral Pathways
pp. 411-417(7)
Authors: Devrim Can, æ#150;zgür; Alyu, Feyza; Turan, Nazlı; æ#150;zdemir, Ahmet

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In vitro Study of Furazano[3,4-b]quinoxaline 1-Oxides as Potential Releasing Agents
pp. 418-421(4)
Authors: I. Stoitsis, Kosmas; Gkizis, Petros; Basgiouraki, Emmanouella; K. Gallos, John; Hadjipavlou-Litina, Dimitra

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Relationship Between Carbapenems Structure and Minimal Inhibitory Concentration Selected Bacterial Strains
pp. 422-428(7)
Authors: Monika, Marczak; Tomasz, Grabowski; Feder, Marcin

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Design, Synthesis and Mode of Action of Some New 2-(4'-aminophenyl) benzothiazole Derivatives as Potent Antimicrobial Agents
pp. 429-437(9)
Authors: Singh, Meenakshi; Kumar Singh, Sudhir; Gangwar, Mayank; Sellamuthu, Satheeshkumar; Nath, Gopal; K. Singh, Sushil

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Accumulation Effects of Salicylic acid Saccharide Carboxylate on the Alkaloids in Catharanthus roseus Cells
pp. 438-440(3)
Authors: Yang, Er-Bing; Wang, Yong; Zang, Hong-Jun; Li, Zheng-Ming; Liu, Xing-Hai

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Endothelium Dependent and Independent Mechanisms of Vasorelaxant Activity of Synthesized 2,5-disubstituted-1,3,4-oxadiazole Derivatives in Rat Thoracic Aorta – Ex vivo and Molecular Docking Studies
pp. 441-450(10)
Authors: Attari, Zenab; Mudgal, Jayesh; G Nayak, Pawan; Krishnadas, Nandakumar; Rajappan, Revathi; Gopalan Kutty, N.

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Despite an Extensive Sequence Analysis Identification of Functional Candidates Amongst Hypothetical Proteins of Neisseria gonorrhoeae
pp. 451-464(14)
Authors: Kumar, Kundan; Prakash, Amresh; Islam, Asimul; Ahmad, Faizan; Imtaiyaz Hassan, Md.

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Sunscreening and Photosensitizing Properties of Coumarins and their Derivatives
pp. 465-474(10)
Authors: Kasperkiewicz, Kinga; Erkiert-Polguj, Anna; Budzisz, Elzbieta

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