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Letters in Drug Design & Discovery publishes original letters on all areas of rational drug design and discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, and structure-activity relationships. The emphasis will be on publishing quality papers very rapidly. Letters will be processed rapidly by taking full advantage of Internet technology for both the submission and review of manuscripts. The journal is essential reading to all pharmaceutical scientists involved in research in drug design and discovery.

Publisher: Bentham Science Publishers

Volume 11, Number 2, February 2014

Articles

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pp. i-vii(7)

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Synthesis of 1-aroyl-3,5-dimethyl-1H-pyrazoles as Anti-HCV and Anticancer Agents
pp. 121-131(11)
Authors: Aydın, Sevil; Kaushik-Basu, Neerja; Özbaş-Turan, Suna; Akbuğa, Jülide; Mega Tiber, Pınar; Orun, Oya; R. Gurukumar, K.; Basu, Amartya; Güniz Küçükgüzel, Ş.

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Synthesis and In Vitro Anticancer Activity of Novel 2-((3-thioureido)carbonyl) phenyl Acetate Derivatives
pp. 132-137(6)
Authors: Xiong, Lin; Gao, Ya-Qin; Niu, Chu-E; Wang, Hong-Bo; Li, Wei-Hong

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Synthesis of Unsymmetrical C5-Curcuminoids as Potential Anticancer Agents
pp. 138-149(12)
Authors: Manohar, Sunny; Thakur, Anuj; I. Khan, Shabana; Sun, Guojing; Ni, Nanting; Wang, Binghe; S. Rawat, Diwan

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Bis-phenylazoneonicotinoids as Divalent Insecticides: Design, Synthesis and Activity
pp. 150-155(6)
Authors: Zhang, Jingwei; Shao, Xusheng; Li, Zhong; Xu, Xiaoyong

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Synthesis of Highly Functionalised Dispiropyrrolidine Derivatives as Novel Acetylcholinesterase Inhibitors
pp. 156-161(6)
Authors: Chee Wei, Ang; Ashraf Ali, Mohamed; Keng Yoon, Yeong; Ismail, Rusli; Soo Choon, Tan; Khaw, Kooi-Yeong; Murugaiyah, Vikneswaran; Sanjeevi Lakshmipathi, Venu

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Correlation Between Structure, Retention and Lipophilicity of Some Antidepressants: QSRR and QSAR Studies
pp. 162-168(7)
Authors: S.Perušković, Danica; R.Stevanović, Nikola; Đ.Lolić, Aleksandar; M.Baošić, Rada

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Antidepressant Activity of 8-(trifluoromethyl)-1,2,3,4,5-benzopentathiepin- 6-amine hydrochloride (TC-2153): Comparison with Classical Antidepressants
pp. 169-173(5)
Authors: V. Kulikov, Alexander; A. Tikhonova, Maria; A. Kulikova, Elizabeth; P. Volcho, Konstantin; M. Khomenko, Tatyana; F. Salakhutdinov, Nariman; K. Popova, Nina

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Modeling of Drug Released from Acyclovir Nanoparticles Based on Artificial Neural Networks
pp. 174-183(10)
Authors: Shahsavari, Shadab; Vasheghani-Farahani, Ebrahim; Ardjmand, Mehdi; Abedin Dorkoosh, Farid

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Cu-mediated synthesis of 2,3-dihydro-1H-pyrrolo[3,2,1-ij]quinolin-1-ones as potential inhibitors of sirtuins
pp. 199-206(8)
Authors: Srinivas Rao, Sreerama; Rambabu, Dandela; Layek, Mohosin; Lalith Kumar, Kummari; Venkata Basaveswara Rao, Mandava; Haldar, Devyani; Pal, Manojit

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Augmenting the Xanthine Oxidase Inhibitory Activity of Febuxostat by its Structural Modification
pp. 207-210(4)
Authors: Chandra Sekhar, Kuruva; Madhava, Golla; Venkata Ramana, Katla; Rama Murthy, CH.; Naga Raju, Chamarthi

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Molecular Modeling and Ligand-Protein Interaction of N-Protein of Chandipura Virus
pp. 211-221(11)
Authors: Chandra Sahoo, Ganesh; Yousuf Ansari, Md.; Rana, Sindhuprava; Ranjan Dikhit, Manas; Kamal Topno, Roshan; Pandey, Krishna; Das, Pradeep

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Synthesis of Novel and Highly Functionalized 4-hydroxycoumarin Chalcone and their Pyrazoline Derivatives as Anti-Tuberculosis Agents
pp. 222-230(9)
Authors: Asad, Mohammad; Beevi, Farzana; Pandian Ganesan, Suresh; Oo, Chuan-Wei; Suresh Kumar, Raju; Laxmipathi, Venu; Osman, Hasnah; Ashraf Ali, Mohamed

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Interaction between Basic 7S Globulin and Leginsulin in Soybean [Glycine max]: A Structural Insight
pp. 231-239(9)
Authors: Singh, Amandeep; Kumar Thakur, Prasoon; Meena, Megha; Kumar, Dhiraj; Bhatnagar, Sonika; K. Dubey, Ashok; Imtaiyaz Hassan, Md.

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Biochemical Changes Evidenced in Alzheimer's Disease: A Mini-Review
pp. 240-248(9)
Authors: Scotti, Luciana; Jaime Bezerra Mendonça Junior, Francisco; Sobral da Silva, Marcelo; R. Pitta, Ivan; Tullius Scotti, Marcus

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