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Antioxidant Capacity of 2-(3,5-diaryl-4,5-dihydro-1H-pyrazol-1-yl)-4-phenylthiazoles

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The antioxidant capacity of 2-(3,5-diaryl-4,5-dihydro-1H-pyrazol-1-yl)-4-phenylthiazoles was evaluated. The values of antioxidant capacities of compounds 2d and 2e were found to be, respectively, 2,700 ± 150 and 3,135 ± 230 TE by the ORAC method, corresponding to a significant antioxidant capacity.

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Keywords: Anticancer agents; Antimicrobial agents; Antineoplastic agents; Antioxidant; Antioxidant Capacity; Antioxidant agents; Antioxidant synthetic; Antioxidants; Blenoxane; Bleomycine; Green chemistry; High throughput assay; Hypotenstive activity; ORAC; ORAC Methodology; Putative antioxidants; Reverse transcriptase inhibitors; Thiazole; Thiazolyl compounds; Tiazofurin; Trolox; α-blocking agents

Document Type: Research Article

Publication date: November 1, 2010

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  • Letters in Drug Design & Discovery publishes original letters on all areas of rational drug design and discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, and structure-activity relationships. The emphasis will be on publishing quality papers very rapidly. Letters will be processed rapidly by taking full advantage of Internet technology for both the submission and review of manuscripts. The journal is essential reading to all pharmaceutical scientists involved in research in drug design and discovery.
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